PATHOGEN
DETECTION
LABORATORY

Road 98 & Hutchison
CNPRC – UC Davis
Davis, CA 95616

530-752-8249

Simian Virus 40 (SV40)

Simian virus 40 is a member of the polyomavirus subgroup of Papovaviridae. SV40 is a common persistent infection in macaques and Green monkeys. It can cause lesions on the kidney and brain in immunodeficient monkeys. It is an opportunistic virus causing progressive multifocal leukoencephalopathy in SIV-infected macaques, and has also been shown to cause mesotheliomas (rare lung tumors), non-Hodgkin’s lymphomas, interstitial nephritis and multifocal leukoencephalopathy in lab animals.

Antibody screening is performed using an enzyme immunoassay using SV40 lysate as the target antigen. The performance characteristics of this assay are currently being determined. Please contact us for current testing status.